Nothing to Hide: Overcoming Plaque Psoriasis

Brandpoint (BPT)
August 10, 2018

(BPT) – Like many psoriasis patients, Kim Knight has tried numerous treatment options over the years to help reduce the red, flaky patches covering the skin on her elbows, hands, knees and scalp. Unlike many people with psoriasis, however, she is lucky enough to work in a dermatology office as a Superficial Radiation Technology Specialist, where she is able to receive the direct advice and support of her office’s healthcare providers.

“I’ve had psoriasis for more than two decades, and growing up in the south near the beach meant I always had to cover up to avoid people staring at me or asking questions,” Kim said. “But working in the dermatology industry and alongside my doctor allows me to get first-hand knowledge on innovative research and access to new treatment options to help my psoriasis.”

Plaque psoriasis is the most common type of psoriasis, a chronic, non-contagious skin disease that alters the life cycle of skin cells, causing them to build up rapidly on the surface of the skin.1,2,3 Depending on the severity of the psoriasis and type, the condition can be treated with a topical treatment, oral drug, or injectable.4 August is Psoriasis Awareness Month, helping to bring attention to the 7.5 million Americans that have psoriasis.5

“We’ve used a range of treatments through the years for Kim’s psoriasis, but found their effects wore off over time,” said Douglas DiRuggiero, physician assistant, in Rome and Cartersville, GA. “During Kim’s most recent flare up, I recommended she try SILIQ, since it works differently than other treatments by blocking a specific group of proteins at the site of inflammation.”6

SILIQ™ (brodalumab) injection is a prescription medicine used to treat adults with moderate-to-severe plaque psoriasis who may benefit from injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light treatment), and who have tried other systemic therapies that didn’t work or stopped working.6 It is not known whether SILIQ is safe and effective in children.

Since being treated with SILIQ, Kim’s psoriasis is under control, and she feels less itching and burning. Individual results may vary.

“It’s been so nice to be able to take trips to the beach with my husband and son without having to cover up. I’m so happy to be able to wear short-sleeves and tank tops this summer!” said Kim.

If you have psoriasis, talk to your health care provider about potential treatment options. For more information about SILIQ, visit www.siliq.com.

Important Safety Information

What is SILIQ?

SILIQTM injection is a prescription medicine used to treat adults with moderate to severe plaque psoriasis:

  • who may benefit from injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light treatment)

and

  • who have tried another systemic therapy that didn’t work or stopped working

It is not known if SILIQ is safe and effective in children.

What is the most important information I should know about SILIQ?

Suicidal thoughts or behavior: Some patients taking SILIQ have had suicidal thoughts or ended their own lives. This risk is higher if you have a history of suicidal thoughts or depression. It is not known if SILIQ causes these thoughts or actions.

Get medical help right away if you or a family member notices that you have any of the following symptoms:

  • new or worsening depression, anxiety, or mood problems
  • thoughts of suicide, dying, or hurting yourself
  • attempt to commit suicide, or acting on dangerous impulses
  • other unusual changes in your behavior or mood

Your healthcare provider will give you a SILIQ patient/wallet card about symptoms that need medical attention right away. Carry the card with you during treatment with SILIQ and show it to all of your healthcare providers.

Serious Infections: SILIQ may lower the ability of your immune system to fight infections and may increase your risk of infections.

  • Your healthcare provider should check you for tuberculosis (TB) before starting treatment with SILIQ and may treat you for TB before starting SILIQ if you have TB or a history of it
  • You and your healthcare provider need to watch closely for signs and symptoms of infection during treatment with SILIQ, including fever, sweats, chills, shortness of breath, stomach issues, muscle aches, cough, sore throat or trouble swallowing, warm/red/painful skin sores, burning while urinating or more frequent urination

Who should not use SILIQ?

Do not use SILIQ if you have Crohn’s disease. Tell your healthcare provider if you develop diarrhea, bloody stools, stomach pain or cramping, sudden or uncontrollable bowel movements, loss of appetite, constipation, weight loss, fever or tiredness as these may be symptoms of Crohn’s disease.

Before starting SILIQ, tell your healthcare provider if you:

  • have a history of mental health problems, including suicidal thoughts, depression, anxiety, or mood problems
  • have an infection that does not go away or keeps coming back
  • have TB or have been in close contact with someone with TB
  • have recently received or are scheduled to receive an immunization (vaccine). You should avoid getting live vaccines while being treated with SILIQ
  • are or plan to become pregnant, or are breastfeeding or plan to do so. It is unknown if SILIQ can harm your unborn or newborn baby

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use SILIQ?

See the detailed “Instructions for Use” that come with your SILIQ for information on the right way to store, prepare, and give your SILIQ injections at home, and how to properly throw away (dispose of) used SILIQ prefilled syringes. Use SILIQ exactly as your healthcare provider tells you to use it.

What are possible side effects of SILIQ?

SILIQ may cause serious side effects. See “What is the most important information I should know about SILIQ?” and “Who should not take SILIQ?”

The most common side effects of SILIQ include: joint pain, muscle pain, headache, injection site reactions, tiredness, flu, diarrhea, low white blood cell count (neutropenia), mouth or throat pain, fungal infections of the skin, nausea.

Call your doctor for medical advice on side effects. You are encouraged to report negative side effects of prescription drugs to FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088. Please click here for accompanying full Prescribing Information, including Boxed Warning about suicidal ideation and behavior, and Medication Guide.

Please click here for full Prescribing Information, including Medication Guide.

SILIQ is a trademark of Ortho Dermatologics’ affiliated entities.

References

  1. National Psoriasis Foundation. (2014). About Psoriasis. Retrieved from https://www.psoriasis.org/about-psoriasis. Accessed February 6, 2018.
  2. World Health Organization. (2016). Psoriasis. Retrieved from http://www.who.int/ncds/management/psoriasis/en/. Accessed February 6, 2018.
  3. Mayo Clinic. (2017). Psoriasis. Retrieved from https://www.mayoclinic.org/diseases-conditions/psoriasis/symptoms-causes/syc-20355840. Accessed February 6, 2018.
  4. Informed Health Online. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Psoriasis: Oral medications and injections. 2017 May 18. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK435704/. Accessed March 29, 2018.
  5. American Academy of Dermatology. Psoriasis: Who Gets and Causes. Retrieved from https://www.aad.org/public/diseases/scaly-skin/psoriasis#causes. Accessed March 30, 2018.
  6. SILIQ [prescribing information]. Bridgewater, NJ: Valeant Pharmaceuticals North America LLC.

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